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Lakin BA, Ellis DJ, Shelofsky JS, Freedman JD, Grinstaff MW, Snyder BD. Contrast-enhanced CT facilitates rapid, non-destructive assessment of cartilage and bone properties of the human metacarpal. Osteoarthritis Cartilage. June 2015.

Publication Date
June 2015

How Analyze was Used
“The baseline μCT data were converted to DICOM format (Scanco Medical) before post processing analysis (Analyze™, AnalyzeDirect, Overland Park, KS). The mean cartilage thickness at the indentation testing was determined (Analyze), and the cartilage of each sample was evaluated using a standard indentation testing procedure.”

Keywords
Bone Density
Cadaver
Cartilage
Cartilage, Articular
Contrast Media
Dimethylmethylene Blue
Humans
Linear Models
Metacarpal Bones
Osteoarthritis
Safranine T
Staining and Labeling
Tomography, X-Ray Computed (CT)
X-Ray Microtomography

Author Affiliation(s)
Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, US. (BAL, DJE, JSS, BDS)

Department of Biomedical Engineering, Boston University, Boston, MA, US. (BAL, JSS, MWG)

Department of Pharmacology and Experimental Therapeutics, Boston University, Boston, MA, US. (JDF)

Department of Chemistry, Boston University, Boston, MA, US. (MWG)

Department of Orthopaedic Surgery, Boston Children’s Hospital, Boston, MA, US. (BDS)

ID# 2693

Tags: Articular Cartilage, Bone Density, Cadaver, Cartilage, Contrast Media, Dimethylmethylene Blue, Humans, Linear Models, Metacarpal Bones, Osteoarthritis, Safranine T, Staining and Labeling, X-Ray Computed Tomography (CT), X-Ray Microtomography