Analyze Publications Database

Brain aging, cognition in youth and old age and vascular disease in the Lothian Birth Cohort 1936: rationale, design and methodology of the imaging protocol

Wardlaw JM, Bastin ME, Valdés Hernández MC, Maniega SM, Royle NA, Morris Z, Clayden JD, Sandeman EM, Eadie E, Murray C, Starr JM, Deary IJ. Brain aging, cognition in youth and old age and vascular disease in the Lothian Birth Cohort 1936: rationale, design and methodology of the imaging protocol. Int J Stroke. December 2011;6(6):547-559.

Full Text – Open Access

Publication Date
December 2011

How Analyze was Used
“A whole-brain mask is initially obtained from the T2*W volume with the Object Extractor Tool from Analyze 10.0 and then edited to remove erroneous tissue by applying it to a fused T1W/T2W or T2*W/FLAIR volume pair produced with MCMxxxVI.”

Keywords
Adolescent
Aged
Aging/physiology
Algorithms
Atrophy
Brain/growth & development
Brain Mapping
Carotid Arteries/ultrasonography
Cerebral Cortex/growth & development/pathology
Cognition/physiology
Cognition Disorders/etiology/psychology
Cohort Studies
Diagnostic Imaging
Diffusion Tensor Imaging
Female
Humans
Image Processing, Computer-Assisted
Longitudinal Studies
Magnetic Resonance Imaging (MRI)
Male
Mental Processes/physiology
Research Design
Risk Factors
Sample Size
Vascular Diseases/epidemiology/psychology
Vertebral Artery/ultrasonography

Author Affiliation(s)
Brain Research Imaging Centre, Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK. (JMW, MEB, MCVH, SMM, NAR, ZM, EMS)

Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh, UK. (JMW, MEB, MCVH, SMM, NAR, ZM, EMS)

Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE), University of Edinburgh, Edinburgh, UK. (JMW, MEB, MCVH, SMM, NAR, CM, JMS, IJD)

Health Sciences (Medical Physics), University of Edinburgh, Edinburgh, UK. (MEB)

Institute of Child Health, University College London, London, UK. (JDC)

Department of Neuroradiology, Western General Hospital, NHS Lothian, Edinburgh, UK. (EE)

Department of Psychology, University of Edinburgh, Edinburgh, UK. (CM, IJD)

Geriatric Medicine Unit, University of Edinburgh, Edinburgh, UK. (JMS)

ID# 722

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