AnalyzeDirect Karnik MS, Wang L, Barch DM, Morris JC, Csernansky JG. BDNF polymorphism rs6265 and hippocampal structure and memory performance in healthy control subjects. Psychiatry Res. July 2010;178(2):425-429.
Full Text – Open Access
Publication Date
July 2010
How Analyze was Used
“MR datasets were reformatted using Analyze™ software (Analyze-AVW, 2004), and signed 16-bit MR datasets were compressed to unsigned 8-bit MR datasets by linearly rescaling voxel intensities such that voxels with intensity levels at two standard deviations above the mean of white matter (corpus callosum) were mapped to 255, and voxels with intensity levels at two standard deviations below the mean of CSF (lateral ventricle) were mapped to 0.”
Keywords
Adult
Aged
Brain-Derived Neurotrophic Factor/genetics
Cohort Studies
Female
Genotype
Hippocampus/anatomy & histology
Humans
Linear Models
Magnetic Resonance Imaging (MRI)/methods
Male
Memory/physiology
Methionine/genetics
Middle Aged
Neuropsychological Tests
Polymorphism, Genetic/genetics
Valine/genetics
Author Affiliation(s)
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, US. (MSK, DMB)
Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg, School of Medicine, Chicago, IL, US. (LW, JGC)
Department of Psychology, Washington University, St. Louis, MO, US. (DMB)
Department of Neurology, Washington University School of Medicine, St. Louis, MO, US. (JCM)
ID# 1167
Tags: /diagnosis/epidemiology, Adult, Amygdala/anatomy & histology, Anxiety Disorders/diagnosis/epidemiology, Comorbidity, Female, Functional Laterality/physiology, Health Status, Humans, Magnetic Resonance Imaging (MRI), Major Depressive Disorder, Male, Remission Induction, Severity of Illness Index