Rustum YM, Tóth K, Seshadri M, Sen A, Durrani FA, Stott E, Morrison CD, Cao S, Bhattacharya A. Architectural heterogeneity in tumors caused by differentiation alters intratumoral drug distribution and affects therapeutic synergy of antiangiogenic organoselenium compound. J Oncol. April 2010;2010:396286.
Full Text – Open Access
Publication Date
April 2010
How Analyze was Used
“Image processing and analysis were carried out using commercially available medical imaging software Analyze PC, Version 7.0 (AnalyzeDirect, Lenexa, KS).”
Keywords
Cell Line, Tumor
Drug Resistance, Neoplasm
Drug Therapy
Genetic Heterogeneity
Mice
Models, Animal
Neoplasms/drug therapy/genetics/physiopathology
Selenium
Tissue Array Analysis
Treatment Outcome
Author Affiliation(s)
Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (YMR, KT, MS, FAD, ES, SC)
Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (AS)
Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (CDM)
Department of Cancer Prevention & Control, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (AB)
ID# 966
Tags: Animal Models, Drug Therapy, Genetic Heterogeneity, Mice, Neoplasm Drug Resistance, Neoplasms/drug therapy/genetics/physiopathology, Selenium, Tissue Array Analysis, Treatment Outcome, Tumor Cell Line