Analyze Publications Database

Architectural heterogeneity in tumors caused by differentiation alters intratumoral drug distribution and affects therapeutic synergy of antiangiogenic organoselenium compound

Rustum YM, Tóth K, Seshadri M, Sen A, Durrani FA, Stott E, Morrison CD, Cao S, Bhattacharya A. Architectural heterogeneity in tumors caused by differentiation alters intratumoral drug distribution and affects therapeutic synergy of antiangiogenic organoselenium compound. J Oncol. April 2010;2010:396286.

Full Text – Open Access

Publication Date
April 2010

How Analyze was Used
“Image processing and analysis were carried out using commercially available medical imaging software Analyze PC, Version 7.0 (AnalyzeDirect, Lenexa, KS).”

Keywords
Cell Line, Tumor
Drug Resistance, Neoplasm
Drug Therapy
Genetic Heterogeneity
Mice
Models, Animal
Neoplasms/drug therapy/genetics/physiopathology
Selenium
Tissue Array Analysis
Treatment Outcome

Author Affiliation(s)
Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (YMR, KT, MS, FAD, ES, SC)

Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (AS)

Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (CDM)

Department of Cancer Prevention & Control, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (AB)

ID# 966

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