AnalyzeDirect Mookadam M, Leske DA, Fautsch MP, Lanier WL, Holmes JM. Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. Mol Vis. November 2005;11:909-915.
Full Text – Open Access
Publication Date
November 2005
How Analyze was Used
“Vascularized and total retinal areas were traced in a masked manner using Analyze image analysis software (version 6.0.3b; AnalyzeDirect, Inc., Lenexa, KS) [Robb 2001] and the ratio of vascular to total retinal area was calculated [Mookadam et al. 2004].”
Keywords
Acidosis/blood/physiopathology
Ammonium Chloride/pharmacology
Animals
Animals, Newborn
Antithyroid Agents/pharmacology
Blood Gas Analysis
Disease Models, Animal
Female
Humans
Hydrogen-Ion Concentration
Infant, Newborn
Insulin-Like Growth Factor I/metabolism
Methimazole/pharmacology
Pregnancy
Radioimmunoassay
Rats
Rats, Sprague-Dawley
Retina/drug effects
Retinal Neovascularization/blood/physiopathology
Retinopathy of Prematurity/blood/physiopathology
Thyroxine/blood
Author Affiliation(s)
Department of Ophthalmology, Mayo Clinic College of Medicine, Rochester, MN, US. (MM, DAL, MPF, JMH)
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN, US. (WLL)
ID# 2111
Tags: Acidosis/blood/physiopathology, Ammonium Chloride/pharmacology, Animal Disease Models, Animals, Antithyroid Agents/pharmacology, Blood Gas Analysis, Female, Humans, Hydrogen-Ion Concentration, Insulin-Like Growth Factor I/metabolism, Methimazole/pharmacology, Newborn Animals, Newborn Infant, Pregnancy, Radioimmunoassay, Rats, Retina/drug effects, Retinal Neovascularization/blood/physiopathology, Retinopathy of Prematurity/blood/physiopathology, Sprague-Dawley Rats, Thyroxine/blood