AnalyzeDirect Yi-En Quek et al. Agreement Between Automated and Manual MRI Volumetry in Alzheimer’s Disease: A Systematic Review and Meta-Analysis JMRI.
Publication Date
December 29, 2021
How Analyze was Used
“The current gold standard method to measuring regional brain volumes on structural MRI is manual segmentation. A well-trained expert manually outlines the region of interest on each MRI slice. Volume is estimated by multiplying the delineated cross-sectional area by the distance between slices. Several commonly used medical image processing programs to conduct manual segmentation include…Analyze (AnalyzeDirect, Overland Park, KS)… Manual segmentation is highly accurate, as the trained expert can take into account anatomical variability and correct for image noise based on neuroanatomical knowledge. When carefully conducted, manual segmentation also exhibits high reliability within and among observers.”
Keywords
Alzheimer’s Disease, Automated segmentation, Manual Segmentation, MRI Volumetry
Author Affiliation(s)
The University of Melbourne, Parkville, Victoria, Australia
