AnalyzeDirect

Alt V, Thormann U, Ray S, Zahner D, Dürselen L, Lips K, El Khassawna T, Heiss C, Riedrich A, Schlewitz G, Ignatius A, Kampschulte M, von Dewitz H, Heinemann S, Schnettler R, Langheinrich A. A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures. Acta Biomater. June 2013;9(6):7035-7042.

Publication Date
June 2013

How Analyze was Used
“Axial cross-sections within the fracture zone were manually identified, traced and the cross-sectional area (mm² ) of new bone formation measured using ANALYZE software (ANALYZE 10.0).”

Keywords
Animals
Bone Substitutes/chemical synthesis
Calcification, Physiologic
Disease Models, Animal
Equipment Design
Equipment Failure Analysis
Female
Femoral Fractures/physiopathology/surgery
Humans
Materials Testing
Osteoporotic Fractures/physiopathology/surgery
Ovariectomy
Rats
Rats, Sprague-Dawley
Tissue Scaffolds
Treatment Outcome

Author Affiliation(s)
Department of Trauma Surgery, University Hospital Giessen-Marburg GmbH, Campus Giessen, Giessen, Germany. (VA, UT, CH, GS, RS)

Laboratory of Experimental Trauma Surgery, Justus Liebig University, Giessen, Germany. (VA, UT, SR, KL, TEK, CH, AR, GS, RS)

Central Animal Laboratory, Justus Liebig University, Giessen, Germany. (DZ)

Institute for Orthopaedic Research and Biomechanics, Centre for Musculoskeletal Research Ulm, Ulm University, Ulm, Germany. (LD, AI)

Department of Radiology, University Hospital Giessen-Marburg GmbH, Campus Giessen, Giessen, Germany. (MK, HvD, AL)

Institute of Material Science, Max Bergmann Center of Biomaterials, TU Dresden, Dresden, Germany. (SH)

ID# 387

Tags: Animal Disease Models, Animals, Bone Substitutes/chemical synthesis, Equipment Design, Equipment Failure Analysis, Female, Femoral Fractures/physiopathology/surgery, Humans, Materials Testing, Osteoporotic Fractures/physiopathology/surgery, Ovariectomy, Physiologic Calcification, Rats, Sprague-Dawley Rats, Tissue Scaffolds, Treatment Outcome