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Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation

Camilleri M, Carlson P, McKinzie S, Grudell A, Busciglio I, Burton D, Baxter K, Ryks M, Zinsmeister AR. Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation. Am J Physiol Gastrointest Liver Physiol. January 2008;294(1):G13-19.

Full Text – Open Access

Publication Date
January 2008

How Analyze was Used
“The stomach was identified in the transaxial SPECT images and separated from background by a semiautomated segmentation algorithm. A three-dimensional rendering of the stomach and its volume was obtained by using the AVW 3.0 … image-processing libraries. The primary end points were fasting and postprandial gastric volume.”

Keywords
Adult
Amidohydrolases/genetics
Cannabinoid Receptor Modulators/metabolism
Endocannabinoids
Female
Gastric Emptying/genetics
Gastrointestinal Diseases/genetics/metabolism/physiopathology
Gastrointestinal Motility/genetics
Gastrointestinal Transit/genetics
Genetic Predisposition to Disease
Genotype
Humans
Male
Middle Aged
Odds Ratio
Phenotype
Polymorphism, Genetic
Questionnaires
Rectum/physiopathology
Research Design
Risk Assessment
Risk Factors
Sensation/genetics
Sensory Thresholds
Severity of Illness Index

Author Affiliation(s)
Clinical Enteric Neuroscience Translational and Epidemiological Research, College of Medicine, Mayo Clinic, Rochester, MN, US. (MC, PC, SM, AG, IB, DB, KB, MR)

Department of Health Sciences Research, Division of Biostatistics, College of Medicine, Mayo Clinic, Rochester, MN, US. (ARZ)

ID# 1508

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