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Smith GI, Atherton P, Villareal DT, Frimel TN, Rankin D, Rennie MJ, Mittendorfer B. Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women. PLoS One. March 2008;3(3):e1875.

Full Text – Open Access

Publication Date
March 2008

How Analyze was Used
“Eight 8-mm-thick axial images, starting 10 cm proximal to the distal edge of the femur, with a 7-mm intersection gap, were acquired and muscle volume in each of the images was determined with … Image Analysis Software (Analyze … software version 7.0 …), which utilizes pixel brightness to distinguish muscle from other tissues.”

Keywords
Aged
Aged, 80 and over
Eukaryotic Initiation Factor-4E/metabolism
Female
Humans
Intestinal Absorption
Male
Muscle Proteins/biosynthesis/metabolism
Phosphorylation
Proto-Oncogene Proteins c-akt/metabolism
Ribosomal Protein S6 Kinases/metabolism
Signal Transduction

Author Affiliation(s)
School of Medicine, Washington University, St. Louis, MO, US. (GIS, DTV, TNF, BM)

School of Graduate Entry Medicine and Health, University of Nottingham, Derby, UK. (PA, DR, MJR)

ID# 1483

Tags: Aged, Aged_80 and over, Eukaryotic Initiation Factor-4E/metabolism, Female, Humans, Intestinal Absorption, Male, Muscle Proteins/biosynthesis/metabolism, Phosphorylation, Proto-Oncogene Proteins c-akt/metabolism, Ribosomal Protein S6 Kinases/metabolism, Signal Transduction