AnalyzeDirect Hashizume R, Ozawa T, Dinca EB, Banerjee A, Prados MD, James CD, Gupta N. A human brainstem glioma xenograft model enabled for bioluminescence imaging. J Neurooncol. January 2010;96(2):151-159.
Full Text – Open Access
Publication Date
January 2010
How Analyze was Used
“For the volumetric assessment of intracranial tumor, tumor regions were identified on serially-sectioned H&E stained slides and digital images of these slides were acquired and organized as volume wrapper files, in which images were in spatial registration. Analyze 7.0 software (AnalyzeDirect, Inc., Overland Park, KS) was used to determine three-dimensional tumor volumes for each set of spatially registered images as a function of pixel dimensions.”
Keywords
Animals
Antineoplastic Agents, Alkylating/therapeutic use
Brain Stem Neoplasms/diagnosis/drug therapy
Cell Line, Tumor
Dacarbazine/analogs & derivatives/therapeutic use
Diagnostic Imaging
Disease Models, Animal
Glioma/diagnosis/drug therapy
Humans
In Situ Nick-End Labeling/methods
Kaplan-Meier Estimate
Luciferases/diagnostic use
Luminescent Agents/diagnostic use
Male
Neoplasm Transplantation/methods
Rats
Rats, Nude
Time Factors
Xenograft Model Antitumor Assays/methods
Author Affiliation(s)
Department of Neurological Surgery, Brain Tumor Research Center, University of California, 505 Parnassus Ave., Room M779, San Francisco, CA 94143-0112, US. (RH, TO, EBD, MDP, CDJ, NG)
Division of Pediatric Oncology, Department of Pediatrics, University of California, San Francisco, CA, US. (AB)
ID# 1070
Tags: Alkylating Antineoplastic Agents/therapeutic use, Animal Disease Models, Animals, Brain Stem Neoplasms/diagnosis/drug therapy, Dacarbazine/analogs & derivatives/therapeutic use, Diagnostic Imaging, Glioma/diagnosis/drug therapy, Humans, In Situ Nick-End Labeling/methods, Kaplan-Meier Estimate, Luciferases/diagnostic use, Luminescent Agents/diagnostic use, Male, Neoplasm Transplantation/methods, Nude Rats, Rats, Time Factors, Tumor Cell Line, Xenograft Model Antitumor Assays/methods