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Posterior cingulate cortex atrophy and regional cingulum disruption in mild cognitive impairment and Alzheimer’s disease

Choo IH, Lee DY, Oh JS, Lee JS, Lee DS, Song IC, Youn JC, Kim SG, Kim KW, Jhoo JH, Woo JI. Posterior cingulate cortex atrophy and regional cingulum disruption in mild cognitive impairment and Alzheimer’s disease. Neurobiol Aging. May 2010;31(5):772-779.

Publication Date
May 2010

How Analyze was Used
“The anatomical boundaries of ERC, hippocampus and PCC were traced manually on T1-weighted images using Analyze AVW 5.0 … by one of the authors (IH.C.), who was blind to diagnosis, sex, or subject demographics.”

Keywords
Aged
Alzheimer Disease/pathology
Analysis of Variance
Atrophy/pathology
Cerebral Cortex/pathology
Chi-Square Distribution
Cognition Disorders/pathology
Female
Gyrus Cinguli/pathology
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Neuropsychological Tests
Patient Selection

Author Affiliation(s)
Department of Neuropsychiatry and Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea. (IHC, DYL, SGK, JIW)

Interdisciplinary Program for Cognitive Science, Seoul National University, Seoul, Republic of Korea. (DYL, DSL, JIW)

Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Republic of Korea. (JSO, JSL, DSL)

Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea. (ICS)

Department of Neuropsychiatry, Kyunggi Provincial Hospital for the Elderly, Yongin, Kyunggi, Republic of Korea. (JCY)

Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Kyunggi, Republic of Korea. (KWK)

Department of Psychiatry, Kangwon National University Hospital, Chuncheon, Kangwon, Republic of Korea. (JHJ)

Neuroscience Research Institute of the Medical Research Center, Seoul National University, Seoul, Republic of Korea. (JIW)

ID# 1061

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