Contractor K, Challapalli A, Barwick T, Winkler M, Hellawell G, Hazell S, Tomasi G, Al-Nahhas A, Mapelli P, Kenny LM, Tadrous P, Coombes RC, Aboagye EO, Mangar S. Use of [11C]choline PET-CT as a noninvasive method for detecting pelvic lymph node status from prostate cancer and relationship with choline kinase expression. Clin Cancer Res. December 2011;17(24):7673-7683.
Full Text – Open Access
Publication Date
December 2011
How Analyze was Used
“Decay corrected images were then viewed using Analyze software (Analyze Version 7 …). From summed images, regions of interest (ROI) were drawn manually around visible tumors in the prostate, and any visible pelvic nodes.”
Keywords
Aged
Aged, 80 and over
Carbon Radioisotopes
Choline/diagnostic use/pharmacokinetics
Choline Kinase/biosynthesis
Humans
Immunohistochemistry
Limit of Detection
Lymph Nodes/pathology/radiography/radionuclide imaging
Lymphatic Metastasis/diagnosis
Magnetic Resonance Imaging (MRI)/methods
Male
Middle Aged
Multimodal Imaging/methods
Neoplasm Staging
Pelvis
Positron-Emission Tomography (PET)
Prospective Studies
Prostate/enzymology/radiography/radionuclide imaging
Prostatic Neoplasms/pathology/radiography/radionuclide imaging
Reproducibility of Results
Tomography, X-Ray Computed (CT)
Author Affiliation(s)
Department of 1Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, Hammersmith and Charing Cross Hospitals, London, UK. (KC, AC, MW, GH, GT, PM, LMK, RCC, EOA, SM)
Radiology/Nuclear medicine, Imperial College London and Imperial College Healthcare NHS Trust, Hammersmith and Charing Cross Hospitals, London, UK. (TB, AAN)
Cellular Pathology, Imperial College London and Imperial College Healthcare NHS Trust, Hammersmith and Charing Cross Hospitals, London, UK. (SH)
Cellular Pathology, Northwest London Hospitals NHS Trust, London, UK. (PT)
ID# 774
Tags: Aged, Aged_80 and over, Carbon Radioisotopes, Choline Kinase/biosynthesis, Choline/diagnostic use/pharmacokinetics, Humans, Immunohistochemistry, Limit of Detection, Lymph Nodes/pathology/radiography/radionuclide imaging, Lymphatic Metastasis/diagnosis, Magnetic Resonance Imaging (MRI)/methods, Male, Middle Aged, Multimodal Imaging/methods, Neoplasm Staging, Pelvis, Positron Emission Tomography (PET), Prospective Studies, Prostate/enzymology/radiography/radionuclide imaging, Prostatic Neoplasms/pathology/radiography/radionuclide imaging, Reproducibility of Results, X-Ray Computed Tomography (CT)