AnalyzeDirect Pavese N, Simpson BS, Metta V, Ramlackhansingh A, Chaudhuri KR, Brooks DJ. [18F]FDOPA uptake in the raphe nuclei complex reflects serotonin transporter availability. A combined [18F]FDOPA and [11C]DASB PET study in Parkinson’s disease. Neuroimage. January 2012;59(2):1080-1084.
Publication Date
January 2012
How Analyze was Used
“Once in ANALYZE format the parametric Ki and ADD images generated from each dynamic scan were visually inspected using ANALYZE software (ANALYZE 8.1).”
Keywords
Aged
Aniline Compounds/diagnostic use/pharmacokinetics
Biological Availability
Dihydroxyphenylalanine/analogs & derivatives/diagnostic use/pharmacokinetics
Female
Humans
Male
Parkinson Disease/metabolism/radionuclide imaging
Positron-Emission Tomography/methods
Radiopharmaceuticals/diagnostic use/pharmacokinetics
Raphe Nuclei/metabolism/radionuclide imaging
Serotonin Plasma Membrane Transport Proteins/metabolism
Sulfides/diagnostic use/pharmacokinetics
Tissue Distribution
Author Affiliation(s)
Centre for Neuroscience, Department of Medicine, Imperial College, London, UK. (NP, BSS, AR, DJB)
National Parkinson Foundation Centre of Excellence, Kings College (Denmark Hill Campus), Lewisham Hospital NHS Trust and Biomedical Research Centre Kings College, London, UK. (VM, KRC)
ID# 555
Tags: Aged, Aniline Compounds/diagnostic use/pharmacokinetics, Biological Availability, Dihydroxyphenylalanine/analogs & derivatives/diagnostic use/pharmacokinetics, Female, Humans, Male, Parkinson Disease/metabolism/radionuclide imaging, Positron-Emission Tomography (PET)/methods, Radiopharmaceuticals/diagnostic use/pharmacokinetics, Raphe Nuclei/metabolism/radionuclide imaging, Serotonin Plasma Membrane Transport Proteins/metabolism, Sulfides/diagnostic use/pharmacokinetics, Tissue Distribution