AnalyzeDirect Aging Effects in the Neocortical Organization of Chimpanzees
Normal aging entails many physical, biological, chemical, and psychological changes and, like the rest of the body, the brain changes with every passing year. Aging affects the brain size, vasculature, and cognition. Studies have shown that the volume of the brain and its weight decline with age at a rate of around 5% per decade after…
Hippocampal Atrophy in Critically Ill Patients
Critically ill patients may suffer delirium, encephalopathy or other neurobehavioral abnormalities, often with lasting effects. This is thought to be a result of systemic inflammation which compromises the blood brain barrier and leads to neural damage. The hippocampus is particularly sensitive to inflammatory and hypoxic change, both common sequelae to acute severe illness and/or chronic…
Changes in White and Gray Matter are Biomarkers of Alzheimer’s Disease Years before Clinical Manifestation
A debilitating disease of the aging mind, Alzheimer’s Disease affects 5 million people over the age of 65 years. Women are affected at a higher rate than men because they tend to live longer. The hallmark lesion of Alzheimer’s is a build up of pertinacious amyloid, resulting in the death of nerve cells and demise…