AnalyzeDirect

Analyze Publications Database

The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study

Vella A, Bock G, Giesler PD, Burton DB, Serra DB, Saylan ML, Deacon CF, Foley JE, Rizza RA, Camilleri M. The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study. Clin Endocrinol (Oxf). November 2008;69(5):737-744.

Full Text – Open Access

Publication Date
November 2008

How Analyze was Used
“Tomographic images were acquired using a large field-of-view, dual-headed gamma camera system. Transaxial images of the stomach were obtained with the SPECT Analy[z]e PC 2.5 … software system.”

Keywords
Adamantane/analogs & derivatives/pharmacology
Cross-Over Studies
Diabetes Mellitus, Type 2/metabolism/pathology
Dipeptidyl-Peptidase IV Inhibitors/pharmacology
Double-Blind Method
Drinking/physiology
Eating/physiology
Enteroendocrine Cells/drug effects/secretion
Fasting/blood/metabolism
Gastric Emptying/drug effects/physiology
Ghrelin/blood
Glucagon-Like Peptide 1/blood
Humans
Hypoglycemic Agents/pharmacology
Middle Aged
Nitriles/pharmacology
Organ Size/drug effects
Placebos
Postprandial Period/drug effects
Pyrrolidines/pharmacology
Satiation/drug effects/physiology
Stomach/drug effects/pathology

Author Affiliation(s)
Divisions of Endocrinology and Metabolism, Mayo Clinic, Rochester, MN, US. (AV, GB, PDG, RAR)

Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, US. (DBB, MC)

Novartis Pharmaceuticals, East Hanover, NJ, US. (DBS, MLS, JEF)

Department of Biomedical Sciences, Panum Institute, Copenhagen, Denmark. (CFD)

ID# 1522

Tags: , , , , , , , , , , , , , , , , , , , , ,