Analyze Publications Database

The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers

McParland BJ, Miller MP, Spinks TJ, Kenny LM, Osman S, Khela MK, Aboagye E, Coombes RC, Hui AM, Cohen PS. The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers. J Nucl Med. October 2008;49(10):1664-1667.

Full Text – Open Access

Publication Date
October 2008

How Analyze was Used
“ROIs were defined on OSEM [ordered-subsets expectation maximization] -reconstructed images and mapped to the corresponding FBP [filtered backprojection] image to extract the 18F activities using ANALYZE analysis software (version 7).”

Keywords
Aged
Arginine/chemistry
Aspartic Acid/chemistry
Azetidines/pharmacokinetics
Female
Glycine/chemistry
Humans
Male
Middle Aged
Peptides/pharmacokinetics
Positron-Emission Tomography (PET)/methods
Pyridines/pharmacokinetics
Radiation Dosage
Radiometry/methods
Radiopharmaceuticals/pharmacokinetics
Tissue Distribution

Author Affiliation(s)
Research and Development, Medical Diagnostics, GE Healthcare Ltd., Amersham, Buckinghamshire, England, UK. (BJM, MPM, MKK, AMH, PSC)

Global Imaging Network, GE Healthcare Medical Diagnostics, Grove Centre, Amersham, Buckinghamshire, England, UK. (BJM)

Hammersmith Imanet Ltd., Hammersmith Hospital, London, England, UK. (TJS, SO)

Department of Oncology, Imperial College Faculty of Medicine, Hammersmith Hospital, London, England, UK. (LMK, EA, RCC)

ID# 1465

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