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Kampschulte M, Gunkel I, Stieger P, Sedding DG, Brinkmann A, Ritman EL, Krombach GA, Langheinrich AC. Thalidomide influences atherogenesis in aortas of ApoE(^-/-)/LDLR (^-/-) double knockout mice: a nano-CT study. Int J Cardiovasc Imaging. April 2014;30(4):795-802.

Full Text – Open Access

Publication Date
April 2014

How Analyze was Used
“A total of 1,084 cross sectional nano-CT images was analyzed. Measurements were performed using the ANALYZE Software packages (ANALYZE 9.0/10.0…). Atherosclerotic plaque can be detected by virtue of the intraluminal encroachment by the plaque as well as the different X-ray attenuation properties (i.e. CT gray scale) that differentiate the plaque from the intraluminal contrast agent and the normal surrounding tissues of the arterial wall.”

Keywords
Angiogenesis
Atherosclerosis
Nano-CT
Thalidomide
Vasa Vasorum

Author Affiliation(s)
Department of Diagnostic and Interventional Radiology, University Hospital Giessen, Klinikstrasse 33, 35385, Giessen, Germany. (MK, IG, AB, GAK)

Department of Cardiology, Angiology and Pneumology, University Hospital ‘Otto-von-Guericke’ Magdeburg, Magdeburg, Germany. (PS)

Department of Internal Medicine I, Cardiology/Angiology, Giessen University Hospital, Giessen, Germany. (PS, DGS)

Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany. (DGS)

Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, MN, US. (ELR)

Department of Radiology, BG Clinic Frankfurt/Main, Frankfurt, Germany. (ACL)

ID# 160

Tags: Angiogenesis, Atherosclerosis, Nano-CT, Thalidomide, Vasa Vasorum