Tag Archives: Photochemotherapy

Synthesis of Tumor-avid Photosensitizer-Gd(III)DTPA conjugates: impact of the number of gadolinium units in T1/T2 relaxivity, intracellular localization, and photosensitizing efficacy

Goswami LN, White WH, 3rd, Spernyak JA, Ethirajan M, Chen Y, Missert JR, Morgan J, Mazurchuk R, Pandey RK. Synthesis of Tumor-avid Photosensitizer-Gd(III)DTPA conjugates: impact of the number of gadolinium units in T1/T2 relaxivity, intracellular localization, and photosensitizing efficacy. Bioconjug Chem. May 2010;21(5):816-827. Full Text – Open Access Publication Date May 2010 How Analyze was…

The vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid improves the antitumor efficacy and shortens treatment time associated with Photochlor-sensitized photodynamic therapy in vivo

Seshadri M, Bellnier DA. The vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid improves the antitumor efficacy and shortens treatment time associated with Photochlor-sensitized photodynamic therapy in vivo. Photochem Photobiol. January 2009;85(1):50-56. Full Text – Open Access Publication Date January 2009 How Analyze was Used “Image processing and analysis was carried out using commercially available software (Analyze PC,…

Light delivery over extended time periods enhances the effectiveness of photodynamic therapy

Seshadri M, Bellnier DA, Vaughan LA, Spernyak JA, Mazurchuk R, Foster TH, Henderson BW. Light delivery over extended time periods enhances the effectiveness of photodynamic therapy. Clin Cancer Res. May 2008;14(9):2796-2805. Full Text – Open Access Publication Date May 2008 How Analyze was Used “Image processing and analysis of MRI data were performed using commercially…

High-field magnetic resonance imaging of the response of human prostate cancer to Pc 4-based photodynamic therapy in an animal model

Fei B, Wang H, Meyers JD, Feyes DK, Oleinick NL, Duerk JL. High-field magnetic resonance imaging of the response of human prostate cancer to Pc 4-based photodynamic therapy in an animal model. Lasers Surg Med. October 2007;39(9):723-730. Full Text – Open Access Publication Date October 2007 How Analyze was Used “We manually segmented the tumor…

Tumor vascular response to photodynamic therapy and the antivascular agent 5,6-dimethylxanthenone-4-acetic acid: implications for combination therapy

Seshadri M, Spernyak JA, Mazurchuk R, Camacho SH, Oseroff AR, Cheney RT, Bellnier DA. Tumor vascular response to photodynamic therapy and the antivascular agent 5,6-dimethylxanthenone-4-acetic acid: implications for combination therapy. Clin Cancer Res. June 2005;11(11):4241-4250. Full Text – Open Access Publication Date June 2005 How Analyze was Used “Image analysis and three-dimensional renderings were done…

Chlorophyll-a analogues conjugated with aminobenzyl-DTPA as potential bifunctional agents for magnetic resonance imaging and photodynamic therapy

Li G, Slansky A, Dobhal MP, Goswami LN, Graham A, Chen Y, Kanter P, Alberico RA, Spernyak J, Morgan J, Mazurchuk R, Oseroff A, Grossman Z, Pandey RK. Chlorophyll-a analogues conjugated with aminobenzyl-DTPA as potential bifunctional agents for magnetic resonance imaging and photodynamic therapy. Bioconjug Chem. January 2005;16(1):32-42. Publication Date January 2005 How Analyze was…