Tag Archives: Mouse models

MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat

Jasmine Chen et al. MYC drives platinum resistant SCLC that is overcome by the dual PI3K-HDAC inhibitor fimepinostat Journal of Experimental & Clinical Cancer Research. Publication Date April 26, 2023 How Analyze was Used “Mice were fitted with a heart rate and respiration monitor (BioVet) and scans gated to maximum expiration. Images were processed with…

Murine models of HRAS-mediated cutaneous skeletal hypophosphatemia syndrome suggest bone as the FGF23 excess source

Diana Ovejero et al. Murine models of HRAS-mediated cutaneous skeletal hypophosphatemia syndrome suggest bone as the FGF23 excess source Journal of Clinical Investigation. Publication Date March 21, 2023 How Analyze was Used “Vertebrae L4-L6 were dissected and scanned using a Scanco µCT 50 at 10 µm resolution, 70 306 kVp, 80 µA, and 300 ms…

Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening

Zahra Khalajzeyqami et al. Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening Plos ONE. Publication Date June 15, 2022 How Analyze was Used “The 3D reconstructed datasets in the expiration phase of the breathing cycle were analysed by the Perkin Elmer Analyze software (Analyze 12.0). A…

MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

Abbie S.Ireland et al. MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate. Cancer Cell. Publication Date May 30, 2020 How Analyze was Used “To determine tumor burden, resulting images were processed with Analyze 11.0 software (Analyze Direct) as described previously (Mollaoglu et al., 2017). Scans were calibrated for Hounsfield…

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

Gurkan Mollaoglu et al. The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment. Immunity. Publication Date October 16 2018 How Analyze was Used “At indicated time points, mice were scanned for 30 s to 2 min under isoflurane anesthesia using a small animal Quantum FX microCT…

In Vivo Mouse Intervertebral Disc Degeneration Model Based on a New Histological Classification

Takashi Ohnishi1, Hideki Sudo2, Koji Iwasaki1, Takeru Tsujimoto1, Yoichi M. Ito3, Norimasa Iwasaki1. In Vivo Mouse Intervertebral Disc Degeneration Model Based on a New Histological Classification. PLoS ONE. August 2016. Full Text – Open Access Publication Date August 2016 How Analyze was Used “A quantitative analysis of the sagittal image slices was also performed by…