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Tag Archives: Loss-of-function

Human Loss-of-Function ZNRF3 Mutation Impairs Adipose Thermogenesis and Drives Subcutaneous Fat Expansion

Ningning Zhang et al. Human Loss-of-Function ZNRF3 Mutation Impairs Adipose Thermogenesis and Drives Subcutaneous Fat Expansion Diabetes. Publication Date August 14, 2026 How Analyze was Used “Microcomputed tomography (CT) imaging was performed on a PerkinElmer Quantum GX instrument at Shanghai Medical College of Fudan University, with quantitative analysis conducted using Caliper Analyze software.” Keywords Loss-of-Function,…

Effects of comorbid chronic kidney disease on late-onset hypophosphatasia mice under treatment with asfotase alfa

Cintia Tokuhara et al. Effects of comorbid chronic kidney disease on late-onset hypophosphatasia mice under treatment with asfotase alfa JBMR Plus. Publication Date April 17, 2026 How Analyze was Used “Reconstructed DICOM files were exported and analyzed using Analyze version 14.0 (AnalyzeDirect, Overland Park, KS, USA).” Keywords Preclinical model, Mouse, Loss-of-function, Hypophosphatasia, Chronic kidney disease,…