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Systemic bone loss, impaired osteogenic activity and type I muscle fiber atrophy in mice with elastase-induced pulmonary emphysema: Establishment of a COPD-related osteoporosis mouse model

Manabu Tsukamoto et al. Systemic bone loss, impaired osteogenic activity and type I muscle fiber atrophy in mice with elastase-induced pulmonary emphysema: Establishment of a COPD-related osteoporosis mouse model. Bone.

Publication Date
October 17 2018

How Analyze was Used
“The bone microstructure parameters in the trabecular bone of L1 and the distal femoral metaphysis were evaluated using Analyze 12.0 software (AnalyzeDirect, Inc., KS, USA) and presented as follows: trabecular bone volume (BV/TV: %), trabecular thickness (Tb.Th: mm), trabecular separation (Tb.Sp: mm), trabecular number (Tb.N: 1/mm), structure model index (SMI), and connectivity density (Conn.D: 1/mm3).”

Keywords
Chronic obstructive pulmonary disease, Histomorphometry, Bone formation, Slow twitch, Muscle wasting

Author Affiliation(s)
University of Occupational and Environmental Health, Kitakyushu, Japan

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