AnalyzeDirect Goswami LN, White WH, 3rd, Spernyak JA, Ethirajan M, Chen Y, Missert JR, Morgan J, Mazurchuk R, Pandey RK. Synthesis of Tumor-avid Photosensitizer-Gd(III)DTPA conjugates: impact of the number of gadolinium units in T1/T2 relaxivity, intracellular localization, and photosensitizing efficacy. Bioconjug Chem. May 2010;21(5):816-827.
Full Text – Open Access
Publication Date
May 2010
How Analyze was Used
“Signal intensities at each repetition time were sampled by taking the mean intensity within regions of interest (ROI’s) using commercially available image processing software (Analyze 7.0, AnalyzeDirect, Overland, KS).”
Keywords
Cell Line, Tumor
Cell Survival/drug effects
Gadolinium DTPA/chemical synthesis/chemistry/pharmacokinetics/pharmacology
Humans
Neoplasms/diagnosis/drug therapy
Photochemotherapy
Photosensitizing Agents/chemical
synthesis/chemistry/pharmacokinetics/pharmacology
Author Affiliation(s)
PDT Center, Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (LNG, WHW, ME, YC, JRM, RKP)
Preclinical Imaging Facility, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (JAS, RM)
Department of Dermatology, Roswell Park Cancer Institute, Buffalo, NY 14263, US. (JM)
ID# 1118
Tags: Cell Survival/drug effects, Gadolinium DTPA/chemical synthesis/chemistry/pharmacokinetics/pharmacology, Humans, Neoplasms/diagnosis/drug therapy, Photochemotherapy, Photosensitizing Agents/chemical synthesis/chemistry/pharmacokinetics/pharmacology, Tumor Cell Line