Analyze Publications Database

Serotonin system gene variants and regional brain volume differences in pediatric OCD

Vanessa M. Sinopoli et al. Serotonin system gene variants and regional brain volume differences in pediatric OCD. Brain Imaging and Behavior.

Publication Date
June 11, 2019

How Analyze was Used
“…using Analyze Direct 11.0 (AnalyzeDirect, Inc., Overland Park, KS) for the ACC and the OFC. This measured regional brain volumes in select structures with a priori evidence of their involvement in OCD, along with the total intracranial volume (ICV) for each subject, in cubic centimeters (cc). Overall, the brain regions we examined were the caudate, the putamen, the striatum (caudate + putamen combined), the thalamus, the ACC, and the OFC. As a result, a total of six regions of interest (ROIs) were examined, with respective parameters for the brain regions outlined further in our past studies.”

Keywords
Obsessive-compulsive disorder, OCD, Serotonin system genes, Neuroimaging, Intermediate phenotype

Author Affiliation(s)
University of Toronto, Toronto, Canada

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