Analyze Publications Database

Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial

Dr Kevin N Sheth1, Jordan J Elm2, Bradley J Molyneaux3, Holly Hinson4, Lauren A Beslow1,5, Gordon K Sze6, Ann-Christin Ostwaldt7, Prof Gregory J del Zoppo8, Prof J Marc Simard9, Sven Jacobson10, Dr W Taylor Kimberly7. Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial. The Lancet, Neurology. August 23 2016.

Publication Date
August 2016

How Analyze was Used
“Imaging measures were ascertained on baseline and follow-up scans with Analyze software (version 11.0) by the masked imaging core based on previous methods”

Keywords
Brain swelling , Large hemispheric infarction, Intravenous glyburide, Randomised double-blind placebo-controlled phase 2 trial

Author Affiliation(s)
1 Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale University School of Medicine, New Haven, CT, USA
2 Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA
3 Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
4 Department of Neurology, Oregon Health Sciences University, Portland, OR, USA
5 Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
6 Department of Radiology, Yale University School of Medicine, New Haven, CT, USA
7 Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Massachusetts General Hospital, Boston, MA, USA
8 Division of Hematology, Department of Medicine, and Department of Neurology, University of Washington, Seattle, WA, USA
9 Department of Neurosurgery, University of Maryland, Baltimore, MD, USA
10 Remedy Pharmaceuticals, New York, NY, USA

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