Analyze Publications Database

Saccadic eye movement characteristics in adult Niemann-Pick Type C disease: relationships with disease severity and brain structural measures

Abel LA, Bowman EA, Velakoulis D, Fahey MC, Desmond P, Macfarlane MD, Looi JC, Adamson CL, Walterfang M. Saccadic eye movement characteristics in adult Niemann-Pick Type C disease: relationships with disease severity and brain structural measures. PLoS One. November 2012;7(11):e50947.

Full Text – Open Access

Publication Date
November 2012

How Analyze was Used
“Pontine and mibrain areas were manually outlined on the mid-sagittal slice, and the respective areas calculated using the image analysis software ANALYZE 10.0…and from the ratio of these mid-sagittal areas the pontine:midbrain ratio was calculated.”

Keywords
Adolescent
Adult
Brain/pathology/physiopathology
Case-Control Studies
Demography
Female
Humans
Male
Middle Aged
Niemann-Pick Disease, Type C/pathology/physiopathology/radiography
Reaction Time/physiology
Saccades/physiology
Severity of Illness Index
Visual Fields/physiology
Young Adult

Author Affiliation(s)
Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia. (EAB, DV, MW)

Neuropsychiatry Unit, Royal Melbourne Hospital, Melbourne, Australia. (DV, MW)

Research Centre for the Neurosciences of Ageing, Academic Unit of Psychological Medicine, Australian National University Medical School, Canberra, Australia. (MDM, JC, LL)

Department of Optometry and Vision Sciences, University of Melbourne, Melbourne, Australia. (LAA, EAB)

Department of Paediatrics, Monash University, Melbourne, Australia. (MCF)

Department of Radiology, Royal Melbourne Hospital, Melbourne, Australia. (PD)

Department of Radiology, University of Melbourne, Melbourne, Australia. (PD)

Murdoch Childrens Research Institute, Parkville, Australia. (CLA)

Melbourne Brain Centre, Royal Melbourne Hospital, Department of Medicine, University of Melbourne, Melbourne, Australia. (EAB)

ID# 612

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