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Kassner A, Sitartchouk I, Thornhill R, Carroll T, Mulay C, Aviv R. Relative recirculation (rR): a potential tool for monitoring blood-brain barrier disruption in secondary progressive multiple sclerosis. Paper presented at: Joint Annual Meeting International Society for Magnetic Resonance in Medicine-European Society for Magnetic Resonance in Medicine and Biology, May 2010; Stockholm.

Full Text – Open Access

Publication Date
May 2010

How Analyze was Used
“All data were analyzed offline, beginning with the PD/T2- and T1-weighted images: gray matter, white matter, and cerebrospinal fluid regions were segmented using a validated parcelation method (SABRE; Semi-Automated Brain Region Extraction) [Dade et al. 2004]. These regions were then imported into Analyze 8.0 on which additional regions of interest (ROIs) corresponding to white matter lesions (areas of PD hyperintensity) were superimposed.”

Keywords
Aged
Aged, 80 and over
Blood-Brain Barrier
Brain
Chronic Disease
Evaluation Studies
Humans
Magnetic Resonance Imaging (MRI)
Middle Aged
Multiple Sclerosis
Statistical Analysis

Author Affiliation(s)
Medical Imaging, University of Toronto, Toronto, Ontario, Canada. (AK, IS, RET, RA)

Physiology and Experimental Medicine, Hospital for Sick Children, Toronto, Ontario, Canada. (AK, RET)

Radiology, Northwestern University, Chicago, IL, US. (TJC)

Neuroradiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. (CM, RA)

ID# 1405

Tags: Aged, Aged_80 and over, Blood-Brain Barrier, Brain, Chronic Disease, Evaluation Studies, Humans, Magnetic Resonance Imaging (MRI), Middle Aged, Multiple Sclerosis, Statistical Analysis