AnalyzeDirect Luis de Castro et al. RANKL inhibition reduces lesional cellularity, Gαs variant expression and enables osteogenic maturation in brous dysplasia Research Square.
Publication Date
May 30, 2023
How Analyze was Used
“Reconstructed images were analyzed with Analyze 14 (AnalyzeDirect, Overland Park KS) and calibrated against hydroxyapatite phantoms with known densities. The volume of interest (VOI) was dened as the distal tibia sector between 500 µm below the bula insertion point and 200 µm above the intermedium. The Smart Trace tool was used to outline the distal tibia every 50 µm in the sagittal direction and then Propagate Objects was used to connect the 2D tracings, semi-automatically segmenting the VOI.”
Keywords
RANKL inhibition, Lesional cellularity, Gαs variant expression, Osteogenic maturation, Brous dysplasia
Author Affiliation(s)
National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA
