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Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss

Driban JB, Lo GH, Lee JY, Ward RJ, Miller E, Pang J, Price LL, McAlindon TE. Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss. BMC Musculoskelet Disord. September 2011;12:217.

Full Text – Open Access

Publication Date
September 2011

How Analyze was Used
“After completion of the manual segmentation cartilage volume (mm3) was calculated using Analyze (intra-tester ICC > 0.99).”

Keywords
Bone Marrow/pathology
Bone Marrow Diseases/etiology/pathology
Cartilage, Articular/pathology
Cross-Sectional Studies
Disease Progression
Female
Femur/pathology/radiography
Humans
Hyaline Cartilage/pathology
Knee Joint/pathology/physiopathology
Longitudinal Studies
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Osteoarthritis, Knee/complications/pathology
Pain Measurement
Severity of Illness Index
Tibia/pathology/radiography

Author Affiliation(s)
Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box #406, Boston, MA 02111, US. (JBD, JYL, TEM)

Section of Immunology, Allergy, and Rheumatology, Michael E. DeBakey VAMC, and Baylor College of Medicine, 1 Baylor Plaza, BCM-285, Houston, TX 77030, US. (GHL)

Department of Radiology, Tufts Medical Center, 800 Washington Street, Box #299, Boston, MA 02111, US. (RJW)

Department of Electrical and Computer Engineering, Tufts University, 216 Halligan Hall, Medford, MA 02155, US. (EM, JP)

Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, 800 Washington Street, Box #63, Boston, MA 02111, US. (LLP)

ID# 690

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