AnalyzeDirect Kenny LM, Vigushin DM, Al-Nahhas A, Osman S, Luthra SK, Shousha S, Coombes RC, Aboagye EO. Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by [18F]fluorothymidine-positron emission tomography imaging: evaluation of analytical methods. Cancer Res. November 2005;65(21):10104-10112.
Full Text – Open Access
Publication Date
November 2005
How Analyze was Used
“From the PET image data, regions of interest on tumor and normal tissues (normal breast tissue) were defined manually using the Analyze image analysis software.”
Keywords
Breast Neoplasms/blood/metabolism/pathology/radionuclide imaging
Cell Growth Processes/physiology
Dideoxynucleosides/blood/diagnostic use/pharmacokinetics
Fluorine Radioisotopes/diagnostic use
Humans
Ki-67 Antigen/metabolism
Positron-Emission Tomography (PET)
Radiopharmaceuticals/blood/diagnostic use/pharmacokinetics
Author Affiliation(s)
Molecular Therapy and PET Oncology Research Group, Imperial College London at the Clinical Sciences Centre, Hammersmith Hospital, London, UK. (LMK, EOA)
Cancer Cell Biology, Imperial College London at the Clinical Sciences Centre, Hammersmith Hospital, London, UK. (DMV, RCC)
Hammersmith Imanet, Hammersmith Hospital, London, UK. (SO, SKL)
Department of Nuclear Medicine, Hammersmith Hospital, London, UK. (AAN)
Department of Pathology, Charing Cross Hospital, Hammersmith Hospitals NHS Trust, London, UK. (SS)
ID# 2070
Tags: Breast Neoplasms/blood/metabolism/pathology/radionuclide imaging, Cell Growth Processes/physiology, Dideoxynucleosides/blood/diagnostic use/pharmacokinetics, Fluorine Radioisotopes/diagnostic use, Humans, Ki-67 Antigen/metabolism, Positron Emission Tomography (PET), Radiopharmaceuticals/blood/diagnostic use/pharmacokinetics