AnalyzeDirect Cyarto EV, Lautenschlager NT, Desmond PM, Ames D, Szoeke C, Salvado O, Sharman MJ, Ellis KA, Phal PM, Masters CL, Rowe CC, Martins RN, Cox KL. Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: the AIBL Active trial. BMC Psychiatry. October 2012;12:167.
Full Text – Open Access
Publication Date
October 2012
How Analyze was Used
“Volumetric analysis of the white matter lesions will be performed at a laboratory equipped with FSL … and Analyze (https://analyzedirect.com) software packages.”
Keywords
Adult
Aged
Brain/pathology/physiopathology
Cognitive Therapy/methods
Disease Progression
Exercise Therapy/methods/standards
Female
Geriatric Assessment
Humans
Magnetic Resonance Imaging (MRI)/instrumentation/methods
Male
Memory Disorders/pathology/physiopathology/therapy
Middle Aged
Mild Cognitive Impairment/physiopathology/prevention & control/therapy
Single-Blind Method
Treatment Outcome
Author Affiliation(s)
National Ageing Research Institute, Melbourne, Australia. (EVC, DA, CS, KAE)
Department of Psychiatry, Academic Unit for Psychiatry of Old Age, St. Vincent’s Health, The University of Melbourne, Melbourne, Australia. (NTL, DA, KAE)
School of Psychiatry and Clinical Neurosciences and Western Australia Centre for Health & Ageing, University of Western Australia, Perth, Australia. (NTL)
Department of Radiology, Royal Melbourne Hospital and The University of Melbourne, Melbourne, Australia. (PD, PMP)
Commonwealth Scientific and Industrial Research Organisation (CSIRO) Preventative Health Flagship, Melbourne, Australia. (CS)
CSIRO Preventative Health Flagship ICT, Royal Brisbane and Women’s Hospital, Brisbane, Australia. (OS)
School of Exercise and Health Sciences, Edith Cowan University, Perth, Australia. (MJS)
Mental Health Research Institute, The University of Melbourne, Melbourne, Australia. (KAE, CLM)
Centre for Neuroscience, The University of Melbourne, Melbourne, Australia. (CLM)
Department of Nuclear Medicine and Centre for PET, Austin Hospital, Melbourne, Australia. (CCR)
School of Medical Sciences, Edith Cowan University, Perth, Australia. (RNM)
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia. (KLC)
ID# 635
Tags: Adult, Aged, Brain/pathology/physiopathology, Cognitive Therapy/methods, Disease Progression, Exercise Therapy/methods/standards, Female, Geriatric Assessment, Humans, Magnetic Resonance Imaging (MRI)/instrumentation/methods, Male, Memory Disorders/pathology/physiopathology/therapy, Middle Aged, Mild Cognitive Impairment/physiopathology/prevention & control/therapy, Single-Blind Method, Treatment Outcome