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Adrian L. Oblak et al. Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice Alzheimer’s & Dementia: Translational Research & Clinical Interventions.

Publication Date
July 22, 2025

How Analyze was Used
“All PET and MRI results were co-registered using a 9 degrees of freedom ridged-body mutual information-based normalized entropy algorithm and mapped to stereotactic mouse brain coordinates using Analyze 12 (AnalyzeDirect, Stilwell KS).”

Keywords
Amyloid, BACE inhibitor, MODEL-AD, Mouse model, Preclinical testing

Author Affiliation(s)
Indiana University School of Medicine, Indianapolis, Indiana, USA