Analyze Publications Database

Progressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula

Nestor PJ, Graham NL, Fryer TD, Williams GB, Patterson K, Hodges JR. Progressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula. Brain. November 2003;126(Pt 11):2406-2418.

Full Text – Open Access

Publication Date
November 2003

How Analyze was Used
“In order to minimize normal inter‐subject variability in resting brain metabolism, PET scans were first normalized to the CMRglc of the cerebellar vermis (nCMRglc) using AnalyzeAVW software.”

Keywords
Aged
Alzheimer Disease/metabolism/psychology
Aphasia, Broca/metabolism/psychology
Aphasia, Primary Progressive/metabolism/psychology/radionuclide imaging
Cerebral Cortex/metabolism/radionuclide imaging
Disease Progression
Female
Follow-Up Studies
Glucose/metabolism
Humans
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Neuropsychological Tests
Tomography, Emission-Computed

Author Affiliation(s)
University of Cambridge, Neurology Unit, Addenbrooke’s Hospital, Cambridge, UK. (PJN, JRH)

Wolfson Brain Imaging Centre, Addenbrooke’s Hospital, Cambridge, UK. (TDF, GBW)

MRC Cognition and Brain Sciences Unit, Cambridge, UK. (NLG, KP, JRH)

ID# 2450

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