AnalyzeDirect Herrmann J, Wohlert C, Saguner AM, Flores A, Nesbitt LL, Chade A, Lerman LO, Lerman A. Primary proteasome inhibition results in cardiac dysfunction. Eur J Heart Fail. June 2013;15(6):614-623.
Full Text – Open Access
Publication Date
June 2013
How Analyze was Used
“The images were reconstructed and analysed using the Analyze® software package… For LV size and systolic function, the endocardial and epicardial borders were traced at end-diastole and end-systole, and the LVEF, stroke volume, and LV mass were calculated.”
Keywords
Adenosine/pharmacology
Animals
Boronic Acids/pharmacology
Capillary Permeability/drug effects
Cardiotonic Agents/pharmacology
Cardiomyopathy
Dipeptides/pharmacology
Dobutamine/pharmacology
Female
Heart/drug effects/physiopathology
Heart Failure
In Situ Nick-End Labeling
Myocardial Perfusion Imaging
Proteasome Endopeptidase Complex/drug effects/metabolism
Proteasome Inhibitors/pharmacology
Stroke Volume/drug effects
Swine
Tomography, X-Ray Computed
Vasodilator Agents/pharmacology
Ventricular Function, Left/drug effects
Author Affiliation(s)
Division of Cardiovascular Diseases, Mayo Clinic Rochester, 200 First Street, SW, Rochester, MN 55905, US.
ID# 270
Tags: Adenosine/pharmacology, Animals, Boronic Acids/pharmacology, Capillary Permeability/drug effects, Cardiomyopathy, Cardiotonic Agents/pharmacology, Dipeptides/pharmacology, Dobutamine/pharmacology, Female, Heart Failure, Heart/drug effects/physiopathology, In Situ Nick-End Labeling, Left/drug effects, Myocardial Perfusion Imaging, Proteasome Endopeptidase Complex/drug effects/metabolism, Proteasome Inhibitors/pharmacology, Stroke Volume/drug effects, Swine, Vasodilator Agents/pharmacology, Ventricular Function, X-Ray Computed Tomography