AnalyzeDirect Parsons MW, Christensen S, McElduff P, Levi CR, Butcher KS, De Silva DA, Ebinger M, Barber PA, Bladin C, Donnan GA, Davis SM. Pretreatment diffusion- and perfusion-MR lesion volumes have a crucial influence on clinical response to stroke thrombolysis. J Cereb Blood Flow Metab. June 2010;30(6):1214-1225.
Full Text – Open Access
Publication Date
June 2010
How Analyze was Used
“All MRI scans were read at the coordinating center by investigators blinded to treatment assignment and clinical outcomes. The DWI lesions were assessed by two independent raters who used standard planimetric software (Analyze 7.0).”
Keywords
Adult
Aged
Carotid Artery Diseases/drug therapy/mortality/radiography
Carotid Artery, Internal/radiography
Diffusion Magnetic Resonance Imaging
Double-Blind Method
Female
Fibrinolytic Agents/therapeutic use
Humans
Infusions, Intravenous
Magnetic Resonance Angiography
Male
Middle Aged
Prospective Studies
Stroke/drug therapy/mortality/radiography
Thrombolytic Therapy
Tissue Plasminogen Activator/therapeutic use
Author Affiliation(s)
Department of Neurology, Hunter Medical Research Institute Centre for Brain and Mental Health Research, John Hunter Hospital, University of Newcastle, Newcastle, New South Wales, Australia. (MWP, PM, CRL)
Department of Radiology, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia. (SC)
Department of Neurology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. (KSB)
Department of Neurology, Singapore General Hospital, Singapore. (DAD)
The Center for Stroke Research Berlin, Charité—Universitätsmedizin Berlin, Germany. (ME)
Department of Medicine, Auckland Hospital, University of Auckland, Auckland, New Zealand. (PAB )
Eastern Health Melbourne Neurosciences, Box Hill, Victoria, Australia. (CB)
National Stroke Research Institute, Austin Health, Melbourne, Victoria, Australia. (GAD)
Department of Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia. (SMD)
ID# 874
Tags: Adult, Aged, Carotid Artery Diseases/drug therapy/mortality/radiography, Diffusion Magnetic Resonance Imaging, Double-Blind Method, Female, Fibrinolytic Agents/therapeutic use, Humans, Internal Carotid Artery/radiography, Intravenous Infusions, Magnetic Resonance Angiography, Male, Middle Aged, Prospective Studies, Stroke/drug therapy/mortality/radiography, Thrombolytic Therapy, Tissue Plasminogen Activator/therapeutic use