M.M.Mulholland et al. Phenotypic and genetic associations between gray matter covariation and tool use skill in chimpanzees (Pan troglodytes): Repeatability in two genetically isolated populations NeuroImage.
May 10, 2022
How Analyze was Used
“Following denoising, the scans were resampled at 0.625 mm isotropic voxels when imported into ANALYZE 11.0 (AnalyzeDirect, Overland Park, Kansas, USA). Then we manually aligned each scan on the Anterior Commissure-Posterior Commissure (AC-PC) axis and saved each in radiological space. To do so, we used a capsule placed during the imaging process as a directional marker for the left and right hemisphere…The volume of each resulting brain region was then measured using the region-of-interest tool in ANALYZE 11.0. We then repeated the SBM analysis described above separately for each colony (NCCC n=139; YNPRC n=77). We then visually inspected the resulting colony specific SBM components for overlap in brain regions. If any components appeared to overlap between the two colonies, we performed a conjunction analysis. To determine the degree of similarity, we binarized and thresholded the component from each colony > 3.0, then added the binary volumes together to determine the regions that were overlapping between these two components.”
Chimpanzee, Source-based morphometry, Tool use, Heritability
The University of Texas MD Anderson Cancer Center, Bastrop, Texas, USA