Analyze Publications Database

Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients

Kenny LM, Coombes RC, Oulie I, Contractor KB, Miller M, Spinks TJ, McParland B, Cohen PS, Hui AM, Palmieri C, Osman S, Glaser M, Turton D, Al-Nahhas A, Aboagye EO. Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients. J Nucl Med. June 2008;49(6):879-886.

Full Text – Open Access

Publication Date
June 2008

How Analyze was Used
“Image analysis was carried out using analysis software (Analyze Version 7 …) as previously reported [Kenny et al. 2005] to obtain time–activity curves.”

Keywords
Adult
Aged
Breast Neoplasms/metabolism/radionuclide imaging
Female
Humans
Metabolic Clearance Rate
Middle Aged
Oligopeptides/metabolism
Organ Specificity
Peptides/adverse effects/diagnostic use/pharmacokinetics
Polyethylene Glycols/adverse effects/diagnostic use/pharmacokinetics
Positron-Emission Tomography/adverse effects/methods
Radiopharmaceuticals/adverse effects/diagnostic use/pharmacokinetics
Tissue Distribution

Author Affiliation(s)
Department of Oncology, Imperial College Faculty of Medicine, Hammersmith Hospital, London, UK. (LMK, RCC, KBC, CP, EOA)

GE Healthcare Medical Diagnostics, Amersham Place, Buckinghamshire, UK. (IO, MM, BP, PSC, AMH, SO, MG, DT)

Department of Nuclear Medicine, Imperial College Faculty of Medicine, Hammersmith Hospital, London, UK. (TJS, AAN)

ID# 1484

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