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Pharmacological modulation of human gastric volumes demonstrated noninvasively using SPECT imaging

Liau SS, Camilleri M, Kim DY, Stephens D, Burton DD, O’Connor MK. Pharmacological modulation of human gastric volumes demonstrated noninvasively using SPECT imaging. Neurogastroenterol Motil. December 2001;13(6):533-542.

Full Text – Open Access

Publication Date
December 2001

How Analyze was Used
“We have previously shown that SPECT-Analyze™ imaging allows in vivo measurement of gastric volume and the meal-induced accommodation response, with low intra- and inter-observer variation [Kuiken et al. 1999]. In the present study, our results validate this novel technique by demonstration of the pharmacological modulation of gastric volumes.”

Keywords
Administration, Sublingual
Adult
Anti-Bacterial Agents/adverse effects/pharmacology
Erythromycin/adverse effects/pharmacology
Fasting/physiology
Female
Humans
Injections, Intravenous
Isosorbide Dinitrate/adverse effects/pharmacology
Male
Middle Aged
Postprandial Period/physiology
Radiopharmaceuticals/diagnostic use
Sodium Pertechnetate Tc 99m/diagnostic use
Stomach/ drug effects/radionuclide imaging
Tomography, Emission-Computed, Single-Photon (SPECT)
Vasodilator Agents/adverse effects/pharmacology

Author Affiliation(s)
Enteric Neuroscience Program, Gastroenterology Research Unit, Mayo Clinic and Mayo Foundation, Rochester, MN, US. (SSL, MC, DYK, DS, DDB)

Section of Nuclear Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN, US. (MKO)

ID# 2736

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