AnalyzeDirect Kamath AV, Williams SP, Bullens S, Cowan KJ, Stenberg Y, Cherry SR, Rendig S, Kukis DL, Griesemer C, Damico-Beyer LA, Bunting S. Pharmacokinetics and biodistribution of a human monoclonal antibody to oxidized LDL in cynomolgus monkey using PET imaging. PLoS One. September 2012;7(9):e45116.
Full Text – Open Access
Publication Date
September 2012
How Analyze was Used
“The 3D images were displayed and quantified using Analyze™ software (AnalyzeDirect; Lenexa, KS).”
Keywords
Animals
Antibodies, Monoclonal/administration & dosage/blood/pharmacokinetics
Female
Heterocyclic Compounds, 1-Ring/pharmacokinetics
Humans
Injections, Intravenous
Lipoproteins, LDL/immunology
Macaca fascicularis/blood/immunology
Male
Positron-Emission Tomography (PET)
Time Factors
Tissue Distribution
Author Affiliation(s)
Genentech Research and Early Development, Genentech, Inc., South San Francisco, CA, US. (AVK, SPW, SB, KJC, LADB, SB)
Bioanalytical and Protein Chemistry, BioInvent International AB, Lund, Sweden. (YS)
Center for Molecular and Genomic Imaging, University of California Davis, Davis, CA, US. (SRC, SR, DLK, CG)
ID# 634
Tags: 1-Ring Heterocyclic Compounds/pharmacokinetics, Animals, Female, Humans, Intravenous Injections, LDL Lipoproteins/immunology, Macaca fascicularis/blood/immunology, Male, Monoclonal Antibodies/administration & dosage/blood/pharmacokinetics, Positron Emission Tomography (PET), Time Factors, Tissue Distribution