AnalyzeDirect Chen YL, Chen PKT, Jeng LB, Huang CS, Yang LC, Chung HY, Chang SCN. Periodontal regeneration using ex vivo autologous stem cells engineered to express the BMP-2 gene: an alternative to alveolaplasty. Gene Ther. November 2008;15(22):1469-1477.
Full Text – Open Access
Publication Date
November 2008
How Analyze was Used
“The three-dimensional computer tomography data were reformed, and the size of the voxel unit was set to 0.27 mm3 [Lo et al, 2000]. Data reformation, image display and measurement of regenerated bone volume were carried out using Analyze 5.0.”
Keywords
Animals
Bone Morphogenetic Protein 2/genetics
Dental Cementum/pathology
Gene Expression
Genetic Therapy/methods
Humans
Imaging, Three-Dimensional
Mesenchymal Stem Cell Transplantation/methods
Mesenchymal Stromal Cells/metabolism
Models, Animal
Periodontal Diseases/pathology/therapy
Periodontium/pathology
Rabbits
Random Allocation
Recombinant Proteins/genetics
Regeneration
Transplantation, Autologous
Author Affiliation(s)
Department of Dentistry, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan. (YLC, CSH)
Department of Plastic Surgery, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan. (PKTC)
Department of Surgery, China Medical University Hospital, Taichung, Taiwan. (LBJ)
School of Medicine, China Medical University, Taichung, Taiwan. (LBJ, SCNC)
Department of Anesthesiology, E-Da Hospital, Kaohsiung, Taiwan. (LCY)
Department of Biological Science and Technology, College of Medical Sciences, I-Shou University, Kaohsiung, Taiwan. (LCY)
Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. (HYC)
Department of Plastic Surgery, China Medical University Hospital, Taichung, Taiwan. (SCNC)
ID# 1494
Tags: Animal Models, Animals, Autologous Transplantation, Bone Morphogenetic Protein 2/genetics, Dental Cementum/pathology, Gene Expression, Genetic Therapy/methods, Humans, Mesenchymal Stem Cell Transplantation/methods, Mesenchymal Stromal Cells/metabolism, Periodontal Diseases/pathology/therapy, Periodontium/pathology, Rabbits, Random Allocation, Recombinant Proteins/genetics, Regeneration, Three-Dimensional Imaging