AnalyzeDirect Michael St. Andre et al. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys. Skeletal Muscle. November 9, 2017.
Publication Date
November 2017
How Analyze was Used
“Analysis of CT scans was conducted off-line from the scanner using the commercial image processing software Analyze (AnalyzeDirect, Overland Park, KS, USA). The aim of the analysis was to quantify longitudinal change in muscle volume over the course of the study period”
Keywords
Myostatin, Hypertrophy, Skeletal muscle, Duchenne muscular dystrophy, Monoclonal antibody, MDX
Author Affiliation(s)
Boston University School of Medicine, Boston, Massachussetts, USA
