Analyze Publications Database

Modulatory effects of perforin gene dosage on pathogen-associated blood-brain barrier (BBB) disruption

Robin C. Willenbring1,2, Fang Jin2, David J. Hinton1,3, Mike Hansen2, Doo-Sup Choi3, Kevin D. Pavelko2 and Aaron J. Johnson2,3. Modulatory effects of perforin gene dosage on pathogen-associated blood-brain barrier (BBB) disruption. Journal of Neuroinflammation. August 31 2016.

Full Text – Open Access

Publication Date
August 2016

How Analyze was Used
“Three-dimensional (3D) volumetric analysis was performed as previously described. In brief, the 3D volume of vascular permeability was quantified using Analyze 10 software.”

Keywords
BBB disruption, CD8 T cells, Perforin, Perforin single nucleotide variants, TMEV, PIFS

Author Affiliation(s)

1 Mayo Graduate School, Mayo Clinic
2 Department of Immunology, Mayo Clinic
3 Department of Neurology, Mayo Clinic

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