AnalyzeDirect John Zagorski et al. Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis Physiological Reports.
Publication Date
January 10, 2022
How Analyze was Used
“For analysis, DICOM image volumes will be imported into Analyze 12.0 (AnalyzeDirect), signal intensity normalized (i.e., [0.0, 1.0]), and tissue segmentation accomplished via segmented threshold for background+soft tissue (i.e., 0.0–0.1) and lung vasculature (i.e., 0.1–1.0). Segmented object maps are then quantified for total vascular volumes using Analyze’s ROI Tool.”
Keywords
Angiogenesis, Cinaciguat, CTEPH, Guanylate cyclase
Author Affiliation(s)
Indiana University School of Medicine, Indianapolis, Indiana, USA
