AnalyzeDirect Whitwell JL, Jack CR, Jr., Parisi JE, Gunter JL, Weigand SD, Boeve BF, Ahlskog JE, Petersen RC, Dickson DW, Josephs KA. Midbrain atrophy is not a biomarker of progressive supranuclear palsy pathology. Eur J Neurol. October 2013;20(10):1417-1422.
Full Text – Open Access
Publication Date
October 2013
How Analyze was Used
“Area of the midbrain was measured manually by one rater (JLW) using Analyze software, based on previously published criteria [Cosottini et al. 2007]. Measurements were performed on the mid-sagittal image with the inferior boundary defined by a line parallel to the conjunction between the genu and splenium of the corpus callosum.”
Keywords
Aged
Aged, 80 and over
Atrophy
Female
Humans
Magnetic Resonance Imaging (MRI)
Male
Mesencephalon/pathology
Midbrain
Middle Aged
Neuropathology
Supranuclear Palsy, Progressive/pathology
Syndrome
Author Affiliation(s)
Department of Radiology, Mayo Clinic, Rochester, MN, US. (JLW, CRJ)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, US. (JEP)
Department of Information Technology, Mayo Clinic, Rochester, MN, US. (JLG)
Department of Health Sciences Research (Biostatistics), Mayo Clinic, Rochester, MN, US. (SDW)
Department of Neurology, Mayo Clinic, Rochester, MN, US. (BFB, JEA, RCP, KAJ)
Department of Neuroscience (Neuropathology), Mayo Clinic, Jacksonville, FL, US. (DWD)
ID# 293
Tags: Aged, Aged_80 and over, Atrophy, Female, Humans, Magnetic Resonance Imaging (MRI), Male, Mesencephalon/pathology, Midbrain, Middle Aged, Neuropathology, Progressive Supranuclear Palsy/pathology, Syndrome