AnalyzeDirect Edison P, Ahmed I, Fan Z, Hinz R, Gelosa G, Ray Chaudhuri K, Walker Z, Turkheimer FE, Brooks DJ. Microglia, amyloid, and glucose metabolism in Parkinson’s disease with and without dementia. Neuropsychopharmacology. May 2013;38(6):938-949.
Full Text – Open Access
Publication Date
May 2013
How Analyze was Used
“We then sampled the [11C](R)PK11195 binding maps and RATIO images using Analyze AVW 8.1 in the following regions: whole cortex, frontal, temporal, parietal and occipital association cortices, anterior and posterior cingulate gyrus, striatum, and thalamus.”
Keywords
Aged
Aged, 80 and over
Amyloid/metabolism
Cohort Studies
Dementia/metabolism/pathology/radionuclide imaging
Female
Glucose/metabolism
Humans
Male
Microglia/metabolism/pathology/radionuclide imaging
Middle Aged
Parkinson Disease/metabolism/pathology/radionuclide imaging
Positron-Emission Tomography (PET)/methods
Author Affiliation(s)
Centre of Neuroscience, Department of Medicine, Imperial College London, London, UK. (PE, IA, ZF, RH, GG, FET, DJB)
Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UK. (RH)
Department of Neurology, University of Milan-Bicocca, Milan, Italy. (GG)
MRC Centre of Neurodegeneration Research, Kings College London, London, UK. (RHC, FET)
Department of Mental Health Sciences, University College London, London, UK. (ZW)
Hammersmith Imanet, GE Healthcare, London, UK. (DJB)
ID# 938
Tags: Aged, Aged_80 and over, Amyloid/metabolism, Cohort Studies, Dementia/metabolism/pathology/radionuclide imaging, Female, Glucose/metabolism, Humans, Male, Microglia/metabolism/pathology/radionuclide imaging, Middle Aged, Parkinson Disease/metabolism/pathology/radionuclide imaging, Positron-Emission Tomography (PET)/methods