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Metformin added to lifestyle intervention for physical function in older adults with obesity (DEMFOS trial): a randomised controlled trial

Maria Liza Duremdes Nava et al. Metformin added to lifestyle intervention for physical function in older adults with obesity (DEMFOS trial): a randomised controlled trial The Lancet Healthy Longevity.

Publication Date
July 31, 2026

How Analyze was Used
“Muscle cross-sectional area for each slice was quantified using AnalyzeDirect software (version 14.0; Mayo Clinic, Rochester, MN, USA), and total muscle volume was calculated as the sum of slice areas.”

Keywords
Obesity, Functional decline, Disability risk, Lifestyle interventions, Metformin

Author Affiliation(s)
Baylor College of Medicine, Houston, Texas, USA

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