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Mediation effects of mean Hounsfield unit on relationship between hemoglobin and expansion of intracerebral hemorrhage

Yong Soo Kim et al. Mediation effects of mean Hounsfield unit on relationship between hemoglobin and expansion of intracerebral hemorrhage Scientific Reports.

Publication Date
August 26, 2021

How Analyze was Used
“After visual inspection of baseline CT scans, all scans taken within 72 h since arrival (n = 493) were analyzed to measure the volume and density (Hounsfield unit, HU) of the hematoma using the Analyze 14.0 software (Analyze Direct, Inc., Overland Park, KS). When multiple CT scans were taken within 72 h, the first CT scan that meets the definition of HE was selected for the analysis. After segmentation of the skull by setting up the lower threshold, ICHs were detected semi-automatically with a density threshold from 44 to 100 HU. HE was defined as relative hematoma growth > 33% or absolute hematoma growth > 6 mL compared with that on the baseline NCCT scan. The relative and absolute volume difference between the maximum volume within 72 h since the arrival and baseline volume of the hematoma was investigated.”

Keywords
Mediation effects, Hounsfield unit, Hemoglobin, Intracerebral hemorrhage

Author Affiliation(s)
Seoul National University Bundang Hospital, Bundang-gu, Seongnam, Gyeonggi-do, Republic of Korea

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