AnalyzeDirect Luby JL, Barch DM, Belden A, Gaffrey MS, Tillman R, Babb C, Nishino T, Suzuki H, Botteron KN. Maternal support in early childhood predicts larger hippocampal volumes at school age. Proc Natl Acad Sci U S A. February 2012;109(8):2854-2859.
Full Text – Open Access
Publication Date
February 2012
How Analyze was Used
“All MR scans were performed on a Siemens 3.0-T Tim Trio dedicated research scanner. Subjects were scanned without sedation in a semistandardized position. Two 3D T1-weighted magnetization prepared rapid gradient echo research-tailored MR scans (1-mm isotropic voxels) were acquired sagittally (repetition time 2,400 ms, echo time 3.16 ms, inversion time 1,200 ms, flip angle 8°, slab 160 mm, 160 partitions, 256 × 256 matrix, field of view 256, total scanning time 12:36). Images were coregistered and averaged to increase signal to noise ratio [Holmes 1998], then 16-bit image data were linearly interpolated to 0.5-mm3 voxels and converted to 8-bit using ANALYZE [Robb 2001].”
Keywords
Adolescent
Child
Child Care
Child, Preschool
Depression/pathology
Female
Hippocampus/anatomy & histology
Humans
Male
Models, Biological
Mothers
Organ Size
Author Affiliation(s)
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110. (JLL, DMB, AB, MSG, RT, CB, TN, HS, KNB)
Department of Psychology, Washington University in St. Louis, St. Louis, MO 63130. (DMB)
Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110. (DMB, KNB)
ID# 642
Tags: Adolescent, Biological Models, Child, Child Care, Depression/pathology, Female, Hippocampus/anatomy & histology, Humans, Male, Mothers, Organ Size, Preschool Child