Analyze Publications Database

Magnetic Resonance investigation into the mechanisms involved in the development of high-altitude cerebral edema

Ravjit S Sagoo1, Charles E Hutchinson1,2, Alex Wright3, Charles Handford4, Helen Parsons5, Victoria Sherwood6, Sarah Wayte6, Sanjoy Nagaraja1, Eddie Ng’Andwe1, Mark H Wilson7, Christopher HE Imray2,8,9. Magnetic Resonance investigation into the mechanisms involved in the development of high-altitude cerebral edema. J Cereb Blood Flow Metab. January 8, 2016.

Publication Date
January 2016

How Analyze was Used
“Analyze 11.0 (AnalyzeDirect, KS, USA) was used to calculate the total volumes of the superior sagittal and transverse venous sinuses using the 3D PC-MRV data acquired at each time point. The semi-automatic threshold technique (using standardized minimum and maximum threshold values) was used to define and extract the appropriate venous sinuses to enable automated volume calculation.

The deep venous space was calculated in by quantifying the total volume of all voxels corresponding with deep veins within the brain tissue, which have low signal intensity on SWI.”

Keywords
Brain imaging
Cerebral blood flow
High altitude
Magnetic resonance imaging
Physiology

Author Affiliation(s)
1 Department of Imaging, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, West Midlands, UK
2 Warwick Medical School, University of Warwick, Coventry, West Midlands, UK
3 College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
4 University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
5 Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, West Midlands, UK
6 Department of Medical Physics, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, West Midlands, UK
7 Department of Neurosurgery, Imperial College Healthcare NHS Trust, London, UK
8 Department of Surgery, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, West Midlands, UK
9 Coventry University, West Midlands, UK

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