AnalyzeDirect Basma A.Ahmed et al. Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota Oxidative Medicine and Cellular Longevity.
Publication Date
September 14, 2021
How Analyze was Used
“Segmentation and analysis of all MRI images were conducted using Analyze Pro (Version 1; Mayo Clinic, Biomedical Imaging Resource, AnalyzeDirect, Overland Park, KS, USA) by a single reader. The SCV was segmented using semi-automated and manual segmentation tools and the accuracy of segmentation was confirmed by an experienced radiologist (NS). The vertebral column was used as the reference for the start (C5-C6 disc) and end (T1-T2 disc) of segmentation. A fat mask, generated from the fat-only images, was first applied to the PDFF map at the C7-T1 disc to isolate adipose tissues and exclude background noise from the MRI image.”
Keywords
Non-alcoholic fatty liver disease, Hepatic fat, Brown adipose tissue, Magnetic resonance imaging, Proton density fat fraction, Microbiota, Germ-free mice, Adult humans, Cold exposure, Fecal transplant
Author Affiliation(s)
McMaster University, Hamilton, Ontario, Canada
