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Loss of serotonergic function in carriers of PRKN mutations: a [11C]DASB PET study

Edoardo Rosario de Natale et al. Loss of serotonergic function in carriers of PRKN mutations: a [11C]DASB PET study European Journal of Nuclear Medicine and Molecular Imaging.

Publication Date
January 29, 2026

How Analyze was Used
“The hypothalamus, caudate, putamen, ventral striatum, thalamus, dorsal raphe, and ventral raphe were manually delineated, using Analyze medical imaging software (v.14.0 Mayo Foundation AnalyzeDirect), on the subjects’ structural T1-weighted MRI.”

Keywords
Parkin mutation, Parkinson’s disease, Serotonin transporter, PET imaging, Non-motor symptoms

Author Affiliation(s)
University of Exeter Medical School, Exeter, UK

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